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What Is Life?: with "Mind and Matter" and "Autobiographical Sketches"
Erwin Schrodinger

Cambridge University Press, 1992 - 194 pages

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A Classic

What is Life? is an absolute classic. Schrodinger felt that life must be explainable by physics and chemistry, yet seemed to violate the normal behavior of entropy-- and he understood further that this was a remarkable wedge point to explore. He figured out the explanation: life is the result of evolution of genetic information, which selects for complex processes that by ordinary considerations would be very unlikely. He predicted that there must be a molecule capable of carrying the genetic information (incorrectly thinking it would be a protein.) His beautifully-written book was influential and timely. Within 4 years, Von Neumann elucidated the mechanisms involved in self-reproducing automata (illustrating his abstract discussion with a picture looking remarkably like DNA to the eyes of readers today); and within a decade, Watson and Crick grasped the structure of DNA. You should not read Schrodinger's book today as one of your first sources to understand life-- there has been remarkable progress in the 50 years since Watson and Crick-- but you should read it to gain appreciation for how science can be advanced when the time is ready and a wedge point, an apparent conflict between fundamental ideas, is analyzed.

The volume also includes another lecture by Schrodinger, Mind and Matter, which is historically interesting in another way. In Schrodinger's day, the state of understanding had not advanced to the point where it was possible to make as useful conjectures about the structure of mind as of life, and he accordingly felt "[mind] may well be beyond human understanding."

Readers interested in Schrodinger's book will also enjoy What is Thought?, published 2004. What is Thought? argues that mind must be explainable by computer science, that the fundamental issues are computational, and that there is again a wedge point: the question of how the workings of a computer, which are always purely syntactical, can correspond to meaning and understanding. The situation is parallel to the one that faced Schrodinger with respect to life in two respects: first, mind is the outcome of evolution, which has built thought processes that seem inconsistent with our standard science, and second, scientific research has advanced to the point where, if we focus on the wedge point, significant understanding is obtainable. What is Thought? brings to bear on the problem of mind core ideas from computational learning theory, complexity theory, and evolutionary computing, as well as molecular and evolutionary biology, cognitive science, and other areas. The result is a principled and concrete explanation, consistent with the vast array of available data, of how meaning, understanding, language, consciousness, and all the various aspects of mind arise from execution of an evolved computer program.


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A physicist's essay on a topic he cannot know as a scientist, only as a human being

I'm wondering why scientists are allowed to give their opinion as scientists about topics they know nothing about as scientists. The beginning of the title ("What is Life") sounds like if Schrodinger can claim anything about the difference between mind and matter as a pure consequence of physics. Too bad, as the rest of the title might make you think that there will be some discussion about why and whether there might be a difference between mind and matter. What remains of mind when you stick to the physics? That would be a very nice question to think about, if only this was the topic of the book...but it's not what is done here.


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Stimulating Reading

Schroedinger, one of the great physicists of the 20th Century, applied the knowledge he gained in his own discipline to analyze human life. Based upon lectures that he gave in the 1940s, this brief book contains Schroedinger's fascinating speculations on the nature of life, several of which have proven prophetic (including the discovery of DNA). The reader comes away with the joy of having shared in the workings of a great mind.

Perhaps the most impressive achievement of the book is that it can be readily understood by persons relatively untrained in science or mathematics.



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An Absolute Classic from a Great Thinker

In "What is Life?" monograph, Schrodinger brilliantly enlightens us with the true concept of life science. He proposes what himself calls "a naive physicist's ideas about organisms." Years before the discovery of double helix structure of DNA, Schrodinger beautifully details how the huge volume of information is related to the structure of what he calls "aperiodic crystal" (what we currently call it "protein structure."

The ideas are still fresh and everybody who really wants to start the REAL and TRUE molecular biology must read this classic. It is astonishing to see how this great thinker and physicist had elaborated, very correctly and properly, to use the statistical tools in physics (statistical physics) to explain the fundamentals of life.

It is an absolute classic from a great legend. Please read and enjoy it.


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It's all there, before the elucidation of DNA via x-rays

This beautiful little book was based on a sequence of popular lectures given in Dublin during WWII, and in turn on an earlier paper given in Vienna. In the book Schrödinger coins the idea of a genetic code carried by linear molecules with his phrase 'code-script'. He asks how, in the absence of validity of a large n limit required by statistical physics for the validity of any macroscopic biological laws, can the chromsome molecules that carry the code-script yield stable genetic rules. Then, he gives the answer: chemical bonding as predicted by quantum theory ala Heitler-London (Schrödinger identifies quantum jumps in the chrosomes as the origin of mutations, which are also discrete). He refers to the chromosome fibers as linear 'aperiodic crystals' (to emphase their stability in the face of thermal fluctuations) and encourages physicists to study them: he boldly asserts that both the instructions and mechanism for generating organisms via molecular replication are contained in the chromosome molecules (and there is where the "complexity" lies). This book encouraged physicists to study problems of complexity long before the term complexity had become the catchword that it is today. Indeed, our first ideas of 'complexity' were developed parallel in the same era by Turing and von Neumann.

Schrödinger is buried in Alpbach (Tirol), where he lectured and enjoyed the Alps frequently after WWII in a school organized by one of two brothers who, according to a very well-informed source, formed nearly the only Resistance in Austria during the war. On his grave is a pretty little plaque bearing the Schrödinger equation.

This review refers to the 1969 edition of 'What is Life'.


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reviews: page 1, 2, 3, 4



Nobel laureate Erwin Schrödinger's What is Life? is one of the great science classics of the twentieth century. A distinguished physicist's exploration of the question which lies at the heart of biology, it was written for the layman, but proved one of the spurs to the birth of molecular biology and the subsequent discovery of the structure of DNA. The philosopher Karl Popper hailed it as a 'beautiful and important book' by 'a great man to whom I owe a personal debt for many exciting discussions'. It appears here together with Mind and Matter, his essay investigating a relationship which has eluded and puzzled philosophers since the earliest times. Schrodinger asks what place consciousness occupies in the evolution of life, and what part the state of development of the human mind plays in moral questions. Brought together with these two classics are Schrödinger's autobiographical sketches, published and translated here for the first time. They offer a fascinating fragmentary account of his life as a background to his scientific writings, making this volume a valuable additon to the shelves of scientist and layman alike.


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