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Explaining 'Unexplained Illnesses': Disease Paradigm for Chronic Fatigue Syndrome, Multiple Chemical ...
Martin L. Pall

Informa HealthCare, 2007 - 446 pages

average customer review:based on 11 reviews
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   highly recommended  highly recommended






technical but useful

This book is technical, which it has to be, but still very useful for the non-biochemist. My purpose was to get ideas for treatment and I got them from the book.


A wealth of Information

Dr. Pall presents The NO/ONOO (pronounced, aptly, "No, oh no!) cycle as the causal mechanism for CFS FM MCS PTSD and related illnesses. Elevated levels of nitric oxide(NO)and its oxidant by-product, peroxynitrite (ONOO) propagate itself and create a chronic vicious cycle.

He says that focus should be on down-regulating the NO/ONOO cycle and presents many modalities collected from various researchers.

There is a wealth of information in this book and a valiant amount of attention to these illnesses, much of it quite technical, but quite understandable for any interested party.

If you have been dealing with and self-researching for ten, twenty years or more, you will find little that you didn't know or haven't tried. A number of sufferers say these modalities fall into 3 categories for them: 1) those that have caused negative effects 2) those that did nothing and 3) those that helped a little for a little while. Others have gotten real help for their condition.

If you are new to this subject, this book is highly informative and well worth reading.


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Thank you, Dr. Pall!

How wonderful it would be if all aspiring physicians were required to read this book! So many in the medical community are not aware of the mystery illnesses which Dr. Pall researches and writes about. If you have Multiple Chemical Sensitivty, Gulf War Syndrome, or Chronic Fatigue Syndrome or you know or love someone who does, then this is the book for you. Dr. Pall's book is well-researched and documented as well as understandable. He's been there so he "gets it," and he offers some help and hope to people who live with these debilitating conditions. Don't miss this book! It's definitely a worthwhile read.


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Helpful Model for Unexplained Illness

Dr. Pall's research and recommended treatment saved me. The core of my treatment for a variety of neurological and digestive problems involves his recommended techniques for down-regulating the NO/ONOO cycle. My improvement relies on specific supplements to turn down reactivity combined with avoidance of chemical and food irritants. I only dared read this book once I had recovered sufficiently to have hope again. Within its pages I found helpful advice, well-supported scientific explanations for my "weird" symptoms and some sobering observations. The lack of recognition of chemical toxicity leads to incredible suffering and financial hardship. Dr. Pall's book should be compulsory reading for every doctor. The biochemical mechanisms he describes should be researched thoroughly so that there can be proven treatments for the growing number of people with "unexplained illness". Also there needs to be increased awareness and regulation of those "harmless" chemicals that are literally destroying lives.



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Thank you, Dr. Pall

I got some information and help, but as someone who reacts to books and ink, it was difficult for me to read. I'd like to see this made available on CD, or electronic version.... and maybe a simplified version for those of us who aren't very technical to begin with. Although, reading it electronically may have cleared some things up for me. I did pass it on to my more technically minded sister, who I'm sure will help me understand.

If you have any of the illnesses that are "unexplained", you really should try to read this. Even if you don't get it all, it may help you some with the direction to move for improvement.

I thank you, Dr. Pall, for your research and writing on this. Blessings on you and yours!


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