This book gathers a collection of refereed articles containing original results reporting the recent contributions of the lectures and communications presented at the Free Boundary Problems Conference that took place at the University of Coimbra, Portugal, from June 7 to 12, 2005 (FBP2005). They deal with the mathematics of a broad class of models and problems involving nonlinear partial differential equations arising in physics, engineering, biology and finance. Among the main topics, the talks considered free boundary problems in biomedicine, in porous media, in thermodynamic modeling, in fluid mechanics, in image processing, in financial mathematics or in computations for inter-scale problems.